Dehydroepiandrosterone (DHEA)
Treatment for Addison's Disease
Typical Dosage: 25-50 mg daily, in the morning
Effectiveness
65%
Safety Score
85%
Clinical Trials
2
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
85
DangerousModerateSafe
Treatment Details
Dosage Range
25-50 mg daily, in the morning
Time to Effect
3-6 months
Treatment Duration
lifetime
Evidence Quality
MODERATENumber Needed to Treat (NNT)
7(Treat 7 patients to see 1 additional successful outcome)
Confidence Score
75%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$300
Monitoring:$50
Side Effect Mgmt:$20
Total Annual:$370
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODQALYs Gained
1.5
Outcome-Based Costs
Cost per Responder
$616.67
Dehydroepiandrosterone (DHEA) Outcomes
for Addison's Disease
Efficacy Outcomes
Overall Effectiveness
+65%
Response Rate
+60%
Common Side Effects
Acne
+8%
Hirsutism
+7%
Oily skin
+6%
Hair loss
+2%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Dehydroepiandrosterone (DHEA) in Addison's Disease
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone Replacement for Primary Adrenal Insufficiency
NCT00004313COMPLETEDPHASE3
40 participants
INTERVENTIONAL
Started: Aug 1, 1995
Survey in Patients With Chronic Adrenal Insufficiency in Germany
NCT00444119COMPLETED
OBSERVATIONAL
Berlin, Germany +1 more
Started: May 1, 2004